powerlab 8sp adinstruments processor Search Results


powerlab system  (ADInstruments)
98
ADInstruments powerlab system
Powerlab System, supplied by ADInstruments, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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powerlab 8sp base  (POWERLAB INC)
90
POWERLAB INC powerlab 8sp base
Powerlab 8sp Base, supplied by POWERLAB INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mls310 hrv module  (ADInstruments)
95
ADInstruments mls310 hrv module
Mls310 Hrv Module, supplied by ADInstruments, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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analog-digital system powerlab 8sp  (POWERLAB INC)
90
POWERLAB INC analog-digital system powerlab 8sp
Analog Digital System Powerlab 8sp, supplied by POWERLAB INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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software chart 5.0  (POWERLAB INC)
90
POWERLAB INC software chart 5.0
Software Chart 5.0, supplied by POWERLAB INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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high-fidelity intraluminal manometry catheter assembly  (POWERLAB INC)
90
POWERLAB INC high-fidelity intraluminal manometry catheter assembly
High Fidelity Intraluminal Manometry Catheter Assembly, supplied by POWERLAB INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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force transducer output  (ADInstruments)
96
ADInstruments force transducer output
Figure 5. Mechanical stress causes myofibrillar degeneration and contraction failure. A, Hematoxylin/eosin staining detects asymmetrical hypertrophy in bag3/ heart. The left 2 images show a low-magnification section of control (bag3/) heart, and the right 2 images depict bag3/ heart. The sagittal and trans- verse sections are displayed in the top and bottom images, respectively. Bar indicates 0.5 mm. B, Myofibrillar degeneration is induced by ex vivo contracture experiment. Papillary muscle fibers (0.4 mm in width and 2 mm in length) were dissected from left ventricles of wild-type, heterozygous, or bag3/ mice. One end of the fibers was tied with monofilament silk to a force <t>transducer</t> (AE801, SensoNor, Horton Norway) and the other to a micromanipula- tor to adjust the muscle length. The fibers were soaked in the high (124 mmol/L) K and low (30 mmol/L) Na solution to facilitate a large caffeine-induced contracture in cardiac muscle. After the sixth con- tracture, the papillary muscle fibers were removed and the myofibrillar ultrastructure was examined. Myofibrillar structure and Z-disc was disrupted in bag3/ papillary muscle after contracture (right) but not in control papillary muscle (left). C, Time course of repeated caffeine contractures in control cardiac muscle fibers. a, Caffeine (20 mmol/L) was repeatedly applied for 3 minutes in the high-K solution, each at 12-minute interval. b shows a rapid deterioration of the repeated caffeine-induced contractures in bag3/ cardiac muscle com- pared to control (bag3/, n4; control, n4). At the sixth contrac- ture, the amplitude was 50% of the original in the bag3/ mus- cle, whereas control muscle maintained 80% amplitude.
Force Transducer Output, supplied by ADInstruments, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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organ chamber  (ADInstruments)
93
ADInstruments organ chamber
Figure 5. Mechanical stress causes myofibrillar degeneration and contraction failure. A, Hematoxylin/eosin staining detects asymmetrical hypertrophy in bag3/ heart. The left 2 images show a low-magnification section of control (bag3/) heart, and the right 2 images depict bag3/ heart. The sagittal and trans- verse sections are displayed in the top and bottom images, respectively. Bar indicates 0.5 mm. B, Myofibrillar degeneration is induced by ex vivo contracture experiment. Papillary muscle fibers (0.4 mm in width and 2 mm in length) were dissected from left ventricles of wild-type, heterozygous, or bag3/ mice. One end of the fibers was tied with monofilament silk to a force <t>transducer</t> (AE801, SensoNor, Horton Norway) and the other to a micromanipula- tor to adjust the muscle length. The fibers were soaked in the high (124 mmol/L) K and low (30 mmol/L) Na solution to facilitate a large caffeine-induced contracture in cardiac muscle. After the sixth con- tracture, the papillary muscle fibers were removed and the myofibrillar ultrastructure was examined. Myofibrillar structure and Z-disc was disrupted in bag3/ papillary muscle after contracture (right) but not in control papillary muscle (left). C, Time course of repeated caffeine contractures in control cardiac muscle fibers. a, Caffeine (20 mmol/L) was repeatedly applied for 3 minutes in the high-K solution, each at 12-minute interval. b shows a rapid deterioration of the repeated caffeine-induced contractures in bag3/ cardiac muscle com- pared to control (bag3/, n4; control, n4). At the sixth contrac- ture, the amplitude was 50% of the original in the bag3/ mus- cle, whereas control muscle maintained 80% amplitude.
Organ Chamber, supplied by ADInstruments, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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octal bridge amplifier  (POWERLAB INC)
90
POWERLAB INC octal bridge amplifier
Figure 5. Mechanical stress causes myofibrillar degeneration and contraction failure. A, Hematoxylin/eosin staining detects asymmetrical hypertrophy in bag3/ heart. The left 2 images show a low-magnification section of control (bag3/) heart, and the right 2 images depict bag3/ heart. The sagittal and trans- verse sections are displayed in the top and bottom images, respectively. Bar indicates 0.5 mm. B, Myofibrillar degeneration is induced by ex vivo contracture experiment. Papillary muscle fibers (0.4 mm in width and 2 mm in length) were dissected from left ventricles of wild-type, heterozygous, or bag3/ mice. One end of the fibers was tied with monofilament silk to a force <t>transducer</t> (AE801, SensoNor, Horton Norway) and the other to a micromanipula- tor to adjust the muscle length. The fibers were soaked in the high (124 mmol/L) K and low (30 mmol/L) Na solution to facilitate a large caffeine-induced contracture in cardiac muscle. After the sixth con- tracture, the papillary muscle fibers were removed and the myofibrillar ultrastructure was examined. Myofibrillar structure and Z-disc was disrupted in bag3/ papillary muscle after contracture (right) but not in control papillary muscle (left). C, Time course of repeated caffeine contractures in control cardiac muscle fibers. a, Caffeine (20 mmol/L) was repeatedly applied for 3 minutes in the high-K solution, each at 12-minute interval. b shows a rapid deterioration of the repeated caffeine-induced contractures in bag3/ cardiac muscle com- pared to control (bag3/, n4; control, n4). At the sixth contrac- ture, the amplitude was 50% of the original in the bag3/ mus- cle, whereas control muscle maintained 80% amplitude.
Octal Bridge Amplifier, supplied by POWERLAB INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ml118 bridge amplifier  (POWERLAB INC)
90
POWERLAB INC ml118 bridge amplifier
Figure 5. Mechanical stress causes myofibrillar degeneration and contraction failure. A, Hematoxylin/eosin staining detects asymmetrical hypertrophy in bag3/ heart. The left 2 images show a low-magnification section of control (bag3/) heart, and the right 2 images depict bag3/ heart. The sagittal and trans- verse sections are displayed in the top and bottom images, respectively. Bar indicates 0.5 mm. B, Myofibrillar degeneration is induced by ex vivo contracture experiment. Papillary muscle fibers (0.4 mm in width and 2 mm in length) were dissected from left ventricles of wild-type, heterozygous, or bag3/ mice. One end of the fibers was tied with monofilament silk to a force <t>transducer</t> (AE801, SensoNor, Horton Norway) and the other to a micromanipula- tor to adjust the muscle length. The fibers were soaked in the high (124 mmol/L) K and low (30 mmol/L) Na solution to facilitate a large caffeine-induced contracture in cardiac muscle. After the sixth con- tracture, the papillary muscle fibers were removed and the myofibrillar ultrastructure was examined. Myofibrillar structure and Z-disc was disrupted in bag3/ papillary muscle after contracture (right) but not in control papillary muscle (left). C, Time course of repeated caffeine contractures in control cardiac muscle fibers. a, Caffeine (20 mmol/L) was repeatedly applied for 3 minutes in the high-K solution, each at 12-minute interval. b shows a rapid deterioration of the repeated caffeine-induced contractures in bag3/ cardiac muscle com- pared to control (bag3/, n4; control, n4). At the sixth contrac- ture, the amplitude was 50% of the original in the bag3/ mus- cle, whereas control muscle maintained 80% amplitude.
Ml118 Bridge Amplifier, supplied by POWERLAB INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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eth200  (iWorx Systems Inc)
90
iWorx Systems Inc eth200
Figure 5. Mechanical stress causes myofibrillar degeneration and contraction failure. A, Hematoxylin/eosin staining detects asymmetrical hypertrophy in bag3/ heart. The left 2 images show a low-magnification section of control (bag3/) heart, and the right 2 images depict bag3/ heart. The sagittal and trans- verse sections are displayed in the top and bottom images, respectively. Bar indicates 0.5 mm. B, Myofibrillar degeneration is induced by ex vivo contracture experiment. Papillary muscle fibers (0.4 mm in width and 2 mm in length) were dissected from left ventricles of wild-type, heterozygous, or bag3/ mice. One end of the fibers was tied with monofilament silk to a force <t>transducer</t> (AE801, SensoNor, Horton Norway) and the other to a micromanipula- tor to adjust the muscle length. The fibers were soaked in the high (124 mmol/L) K and low (30 mmol/L) Na solution to facilitate a large caffeine-induced contracture in cardiac muscle. After the sixth con- tracture, the papillary muscle fibers were removed and the myofibrillar ultrastructure was examined. Myofibrillar structure and Z-disc was disrupted in bag3/ papillary muscle after contracture (right) but not in control papillary muscle (left). C, Time course of repeated caffeine contractures in control cardiac muscle fibers. a, Caffeine (20 mmol/L) was repeatedly applied for 3 minutes in the high-K solution, each at 12-minute interval. b shows a rapid deterioration of the repeated caffeine-induced contractures in bag3/ cardiac muscle com- pared to control (bag3/, n4; control, n4). At the sixth contrac- ture, the amplitude was 50% of the original in the bag3/ mus- cle, whereas control muscle maintained 80% amplitude.
Eth200, supplied by iWorx Systems Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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blood pressure  (ADInstruments)
97
ADInstruments blood pressure
Figure 5. Mechanical stress causes myofibrillar degeneration and contraction failure. A, Hematoxylin/eosin staining detects asymmetrical hypertrophy in bag3/ heart. The left 2 images show a low-magnification section of control (bag3/) heart, and the right 2 images depict bag3/ heart. The sagittal and trans- verse sections are displayed in the top and bottom images, respectively. Bar indicates 0.5 mm. B, Myofibrillar degeneration is induced by ex vivo contracture experiment. Papillary muscle fibers (0.4 mm in width and 2 mm in length) were dissected from left ventricles of wild-type, heterozygous, or bag3/ mice. One end of the fibers was tied with monofilament silk to a force <t>transducer</t> (AE801, SensoNor, Horton Norway) and the other to a micromanipula- tor to adjust the muscle length. The fibers were soaked in the high (124 mmol/L) K and low (30 mmol/L) Na solution to facilitate a large caffeine-induced contracture in cardiac muscle. After the sixth con- tracture, the papillary muscle fibers were removed and the myofibrillar ultrastructure was examined. Myofibrillar structure and Z-disc was disrupted in bag3/ papillary muscle after contracture (right) but not in control papillary muscle (left). C, Time course of repeated caffeine contractures in control cardiac muscle fibers. a, Caffeine (20 mmol/L) was repeatedly applied for 3 minutes in the high-K solution, each at 12-minute interval. b shows a rapid deterioration of the repeated caffeine-induced contractures in bag3/ cardiac muscle com- pared to control (bag3/, n4; control, n4). At the sixth contrac- ture, the amplitude was 50% of the original in the bag3/ mus- cle, whereas control muscle maintained 80% amplitude.
Blood Pressure, supplied by ADInstruments, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Figure 5. Mechanical stress causes myofibrillar degeneration and contraction failure. A, Hematoxylin/eosin staining detects asymmetrical hypertrophy in bag3/ heart. The left 2 images show a low-magnification section of control (bag3/) heart, and the right 2 images depict bag3/ heart. The sagittal and trans- verse sections are displayed in the top and bottom images, respectively. Bar indicates 0.5 mm. B, Myofibrillar degeneration is induced by ex vivo contracture experiment. Papillary muscle fibers (0.4 mm in width and 2 mm in length) were dissected from left ventricles of wild-type, heterozygous, or bag3/ mice. One end of the fibers was tied with monofilament silk to a force transducer (AE801, SensoNor, Horton Norway) and the other to a micromanipula- tor to adjust the muscle length. The fibers were soaked in the high (124 mmol/L) K and low (30 mmol/L) Na solution to facilitate a large caffeine-induced contracture in cardiac muscle. After the sixth con- tracture, the papillary muscle fibers were removed and the myofibrillar ultrastructure was examined. Myofibrillar structure and Z-disc was disrupted in bag3/ papillary muscle after contracture (right) but not in control papillary muscle (left). C, Time course of repeated caffeine contractures in control cardiac muscle fibers. a, Caffeine (20 mmol/L) was repeatedly applied for 3 minutes in the high-K solution, each at 12-minute interval. b shows a rapid deterioration of the repeated caffeine-induced contractures in bag3/ cardiac muscle com- pared to control (bag3/, n4; control, n4). At the sixth contrac- ture, the amplitude was 50% of the original in the bag3/ mus- cle, whereas control muscle maintained 80% amplitude.

Journal: Circulation Research

Article Title: BAG3 and Hsc70 Interact With Actin Capping Protein CapZ to Maintain Myofibrillar Integrity Under Mechanical Stress

doi: 10.1161/circresaha.110.225649

Figure Lengend Snippet: Figure 5. Mechanical stress causes myofibrillar degeneration and contraction failure. A, Hematoxylin/eosin staining detects asymmetrical hypertrophy in bag3/ heart. The left 2 images show a low-magnification section of control (bag3/) heart, and the right 2 images depict bag3/ heart. The sagittal and trans- verse sections are displayed in the top and bottom images, respectively. Bar indicates 0.5 mm. B, Myofibrillar degeneration is induced by ex vivo contracture experiment. Papillary muscle fibers (0.4 mm in width and 2 mm in length) were dissected from left ventricles of wild-type, heterozygous, or bag3/ mice. One end of the fibers was tied with monofilament silk to a force transducer (AE801, SensoNor, Horton Norway) and the other to a micromanipula- tor to adjust the muscle length. The fibers were soaked in the high (124 mmol/L) K and low (30 mmol/L) Na solution to facilitate a large caffeine-induced contracture in cardiac muscle. After the sixth con- tracture, the papillary muscle fibers were removed and the myofibrillar ultrastructure was examined. Myofibrillar structure and Z-disc was disrupted in bag3/ papillary muscle after contracture (right) but not in control papillary muscle (left). C, Time course of repeated caffeine contractures in control cardiac muscle fibers. a, Caffeine (20 mmol/L) was repeatedly applied for 3 minutes in the high-K solution, each at 12-minute interval. b shows a rapid deterioration of the repeated caffeine-induced contractures in bag3/ cardiac muscle com- pared to control (bag3/, n4; control, n4). At the sixth contrac- ture, the amplitude was 50% of the original in the bag3/ mus- cle, whereas control muscle maintained 80% amplitude.

Article Snippet: The force transducer output was digitized using PowerLab/8SP (ADInstruments, Colorado Springs, Colo).

Techniques: Staining, Control, Ex Vivo